dropping a good set of rods and pistons in it can't hurt it at all, there are certain sacrifices made with forged pistons (the biggest being the amount of expansion they have) but if you start getting detonation they tend to hold up better. If I remember correctly the denser metal in a forged piston may not even heat up as much as standard cast pistons, thereby reducing detonatio risk slightly. far as it goes a set of TRW pistons and Eagle rods or better components would be good money in my book, well as a few other more minor things like studs for the mains and heads as well as good ARP rod bolts. If you're wanting to go all out main caps are a good idea, but with what you're running probably not necessary. As far as it goes, detonation is the biggest enemy of these engines, so having a bottom end that'll hold up decently is critical. My thought is that if you've got the motor out and you're considering something do it "while you were at it" do it because it's easier now then when the engine's in the truck.